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Ultra-Low Contrast Angiography

What is Ultra-Low Contrast Angiography?

Ultra-low contrast angiography is a novel technique performed in interventional cardiology and nephrology that utilizes new intravascular invasive technology and non-invasive contrast-sparing techniques. There are two types: ultra-low contrast percutaneous coronary intervention (ULC-PCI) and zero-contrast PCI.

A primary objective of ultra-low-contrast angiography is to minimize contrast exposure and potentially use the least toxic contrast agents to reduce the risk of developing postprocedural contrast-induced nephropathy (CIN), predominantly affecting patients with baseline systemic dysfunctions.

How is Ultra-Low Contrast Angiography performed?

Here are some techniques used during ULC angiography, including:

 

  • Low-osmolar contrast medium for clear imaging.
  • Intravascular ultrasound for imaging guidance and to reduce the contrast load.
  • Intravenous volume hydration reduces the contrast concentration and increases the blood flow.
  • Using small volumes of contrast dye with small catheters to improve visualization.
  • Using multiple guide wires, such as the side branch wire, the marking wire technique.
  • Using coronary calcium as the guideline to locate and trace coronary artery ostia.
  • Increase frame rates to 30 frames per second or higher for improved visualization.

Advantages of Ultra-Low Contrast Angiography

 

  • Affordable, effective, and safe in various clinical settings.
  • Reduced the risk of contrast-induced nephropathy.
  • Minimizes the need for large volumes of contrast injections.
  • Time-efficient procedure.
  • Visualizes even subtle calcifications on the vascular wall.
  • Imaging can be performed from multiple directions.

Clinical Indications for Ultra-Low Contrast Angiography

 

  • Patients with pre-existing chronic kidney disease.
  • Cardiogenic shock.
  • Contrast dye anaphylaxis.
  • Complex, high-risk coronary disease.
  • Iatrogenic or spontaneous coronary dissection.
  • Chronic total occlusions.

Our goal is to preserve the patient’s quality of life through intricate, minimally invasive, and non-invasive methods and preserve the patient’s well-being.

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